• The successful candidate will utilize innovative analytical characterization technologies to drive late-stage pharmaceutical drug product development and commercialization

The Associate Principal Scientist responsibilities include, but not limited to, analytical method development and validation, drug product testing and analytical investigations in a cGMP environment, drug product and manufacturing process characterization, drug product stability studies, specification development, manufacturing process scale-up and validation support, preparation of Chemistry, Manufacturing, and Controls (CMC) documents for global regulatory submissions, and responses to regulatory questions

• The successful candidate must be able to collaborate in a dynamic, integrated, and multidisciplinary team environment

This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely

• The ideal candidate will have knowledge and proficiency in the following areas: separation techniques and aerosol science
• Applicants must have effective organizational skills, multi-tasking, oral and written communications skills

Education Minimum Requirements: PhD in Analytical Chemistry or related discipline with 4+ years of relevant pharmaceutical development experience or MS in Analytical Chemistry or related discipline with 10+ years of relevant pharmaceutical development experience

• Experience with inhalation product characterization including aerodynamic particle size distribution (APSD), delivered dose uniformity (DDU), metered dose uniformity (MDU) and particle size distribution (PSD)
• Strong chemistry knowledge
• Demonstrated problem solving ability
• Excellent verbal and written communication skills, demonstrated creativity, and strong interpersonal skills

Ability to work in a team environment with cross-functional interactions

Strong background and extensive hands-on experience with common analytical techniques such as Ultrahigh/High Performance Liquid Chromatography (UHPLC/HPLC), Gas Chromatography, Ultraviolet (UV) and Infrared (IR) spectroscopy, Karl Fischer titration, and dissolution Analytical Chemistry, Analytical Development, Chemical Biology, Chemical Processing, Chemical Synthesis, Chromatography, Computational Chemistry, Data Analysis, Enzymology, Experimental Development, Gas Chromatography Analysis, Gas Chromatography-Mass Spectrometry (GC-MS), High-Performance Liquid Chromatography (HPLC), Infrared Spectroscopy, Karl Fischer Titrations, Machine Learning (ML), Molecular Structure, Pharmaceutical Development, Spectrophotometry, Synthetic Chemistry

$142,400.00 - $224,100.00 An employee’s position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs

• The successful candidate will be eligible for annual bonus and long-term incentive, if applicable
• We offer a comprehensive package of benefits
• Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days

More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits